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Nanopore sequencing of an expanded genetic alphabet reveals high-fidelity replication of a predominantly hydrophobic unnatural base pair

Unnatural base pairs (UBPs) have been developed and used for a variety of in vitro applications, as well as for the engineering of semi-synthetic organisms (SSOs) that store and retrieve increased information. However, these applications are limited by the availability of methods to rapidly and accu...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Ledbetter, Michael P., Craig, Jonathan M., Karadeema, Rebekah J., Noakes, Matthew T., Kim, Hwanhee C., Abell, Sarah J., Huang, Jesse R., Anderson, Brooke A., Krishnamurthy, Ramanarayanan, Gundlach, Jens H., Romesberg, Floyd E.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263177/
https://ncbi.nlm.nih.gov/pubmed/31985216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b09808
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