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Systematic exploration of a class of hydrophobic unnatural base pairs yields multiple new candidates for the expansion of the genetic alphabet

We have developed a family of unnatural base pairs (UBPs), which rely on hydrophobic and packing interactions for pairing and which are well replicated and transcribed. While the pair formed between d5SICS and dNaM (d5SICS-dNaM) has received the most attention, and has been used to expand the geneti...

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Main Authors: Dhami, Kirandeep, Malyshev, Denis A., Ordoukhanian, Phillip, Kubelka, Tomáš, Hocek, Michal, Romesberg, Floyd E.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176363/
https://ncbi.nlm.nih.gov/pubmed/25122747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku715
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