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Discovery, Characterization, and Optimization of an Unnatural Base Pair for Expansion of the Genetic Alphabet

DNA is inherently limited by its four natural nucleotides. Efforts to expand the genetic alphabet, by addition of an unnatural base pair, promise to expand the biotechnological applications available for DNA as well as being an essential first step towards expansion of the genetic code. We have cond...

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Detalhes bibliográficos
Main Authors: Leconte, Aaron M., Hwang, Gil Tae, Matsuda, Shigeo, Capek, Petr, Hari, Yoshiyuki, Romesberg, Floyd E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892755/
https://ncbi.nlm.nih.gov/pubmed/18217762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja078223d
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