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Minor Groove Hydrogen-Bonds and the Replication of Unnatural Base Pairs

As part of an effort to expand the genetic alphabet, we examined the synthesis of DNA with six different unnatural nucleotides bearing methoxy-derivatized nucleobase analogs. Different nucleobase substitution patterns were used to systematically alter the nucleobase electronics, sterics, and hydroge...

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Autori principali: Matsuda, Shigeo, Leconte, Aaron M., Romesberg, Floyd E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527036/
https://ncbi.nlm.nih.gov/pubmed/17411040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja068282b
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