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Minor Groove Hydrogen-Bonds and the Replication of Unnatural Base Pairs
As part of an effort to expand the genetic alphabet, we examined the synthesis of DNA with six different unnatural nucleotides bearing methoxy-derivatized nucleobase analogs. Different nucleobase substitution patterns were used to systematically alter the nucleobase electronics, sterics, and hydroge...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2527036/ https://ncbi.nlm.nih.gov/pubmed/17411040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja068282b |
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