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Optimization of Unnatural Base Pair Packing for Polymerase Recognition

As part of an effort to expand the genetic alphabet, we have been examining the ability of predominately hydrophobic nucleobase analogs to pair in duplex DNA and during polymerase-mediated replication. We previously reported the synthesis and thermal stability of unnatural base pairs formed between...

詳細記述

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書誌詳細
主要な著者: Matsuda, Shigeo, Henry, Allison A., Romesberg, Floyd E.
フォーマット: Artigo
言語:Inglês
出版事項: 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536690/
https://ncbi.nlm.nih.gov/pubmed/16683801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja057575m
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