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Optimization of Unnatural Base Pair Packing for Polymerase Recognition
As part of an effort to expand the genetic alphabet, we have been examining the ability of predominately hydrophobic nucleobase analogs to pair in duplex DNA and during polymerase-mediated replication. We previously reported the synthesis and thermal stability of unnatural base pairs formed between...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2536690/ https://ncbi.nlm.nih.gov/pubmed/16683801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja057575m |
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