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The effects of unnatural base pairs and mispairs on DNA duplex stability and solvation
In an effort to develop unnatural DNA base pairs we examined six pyridine-based nucleotides, d3MPy, d4MPy, d5MPy, d34DMPy, d35DMPy and d45DMPy. Each bears a pyridyl nucleobase scaffold but they are differentiated by methyl substitution, and were designed to vary both inter- and intra-strand packing...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2724283/ https://ncbi.nlm.nih.gov/pubmed/19515938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp467 |
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