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Reprograming the replisome of a semi-synthetic organism for the expansion of the genetic alphabet

Semi-synthetic organisms (SSOs) created from Escherichia coli can replicate a plasmid containing an unnatural base pair (UBP) formed between the synthetic nucleosides dNaM and dTPT3 (dNaM-dTPT3) when the corresponding unnatural triphosphates are imported via expression of a nucleoside triphosphate t...

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Detalles Bibliográficos
Publicado en:J Am Chem Soc
Autores principales: Ledbetter, Michael P., Karadeema, Rebekah J., Romesberg, Floyd E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5793209/
https://ncbi.nlm.nih.gov/pubmed/29309130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b11488
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