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Expansion of the Genetic Code via Expansion of the Genetic Alphabet

Current methods to expand the genetic code enable site-specific incorporation of non-canonical amino acids (ncAAs) into proteins in eukaryotic and prokaryotic cells. However, current methods are limited by the number of codons possible, their orthogonality, and possibly their effects on protein synt...

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Bibliografische gegevens
Gepubliceerd in:Curr Opin Chem Biol
Hoofdauteurs: Dien, Vivian T., Morris, Sydney E., Karadeema, Rebekah J., Romesberg, Floyd E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361380/
https://ncbi.nlm.nih.gov/pubmed/30205312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2018.08.009
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