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Expansion of the Genetic Code via Expansion of the Genetic Alphabet

Current methods to expand the genetic code enable site-specific incorporation of non-canonical amino acids (ncAAs) into proteins in eukaryotic and prokaryotic cells. However, current methods are limited by the number of codons possible, their orthogonality, and possibly their effects on protein synt...

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Detalles Bibliográficos
Publicado en:Curr Opin Chem Biol
Main Authors: Dien, Vivian T., Morris, Sydney E., Karadeema, Rebekah J., Romesberg, Floyd E.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361380/
https://ncbi.nlm.nih.gov/pubmed/30205312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2018.08.009
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