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Progress Toward a Semi-Synthetic Organism with an Unrestricted Expanded Genetic Alphabet
We have developed a family of unnatural base pairs (UBPs), exemplified by the pair formed between dNaM and dTPT3, for which pairing is mediated not by complementary hydrogen bonding, but by hydrophobic and packing forces. These UBPs enabled the creation of the first semi-synthetic organisms (SSOs) t...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6373772/ https://ncbi.nlm.nih.gov/pubmed/30418780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b08416 |
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