A Semi-Synthetic Organism with an Expanded Genetic Alphabet

Organisms are defined by the information encoded in their genomes, and since the evolution of life, this information has been encoded using a two base pair genetic alphabet (A-T and G-C). In vitro, the alphabet has been expanded to include several unnatural base pairs (UBPs)(1–3). We have developed...

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Bibliografiske detaljer
Main Authors: Malyshev, Denis A., Dhami, Kirandeep, Lavergne, Thomas, Chen, Tingjian, Dai, Nan, Foster, Jeremy M., Corrêa, Ivan R., Romesberg, Floyd E.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058825/
https://ncbi.nlm.nih.gov/pubmed/24805238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13314
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