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Progress Toward Eukaryotic Semi-Synthetic Organisms: Translation of Unnatural Codons
We have created a bacterial semi-synthetic organism (SSO) that retains an unnatural base pair (UBP) in its DNA, transcribes it into mRNA and tRNA with cognate unnatural codons and anticodons, and after the tRNA is charged with a non-canonical amino acid, synthesizes proteins containing the non-canon...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6946121/ https://ncbi.nlm.nih.gov/pubmed/31841336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b09080 |
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