Optimization of Replication, Transcription, and Translation in a Semi-Synthetic Organism

Previously, we reported the creation of a semi-synthetic organism (SSO) that stores and retrieves increased information by virtue of stably maintaining an unnatural base pair (UBP) in its DNA, transcribing the corresponding unnatural nucleotides into the codons and anticodons of mRNAs and tRNAs, and...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Feldman, Aaron W., Dien, Vivian T., Karadeema, Rebekah J., Fischer, Emil C., You, Yanbo, Anderson, Brooke A., Krishnamurthy, Ramanarayanan, Chen, Jason S., Li, Lingjun, Romesberg, Floyd E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693872/
https://ncbi.nlm.nih.gov/pubmed/31241334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b02075
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