Optimization of Replication, Transcription, and Translation in a Semi-Synthetic Organism

Previously, we reported the creation of a semi-synthetic organism (SSO) that stores and retrieves increased information by virtue of stably maintaining an unnatural base pair (UBP) in its DNA, transcribing the corresponding unnatural nucleotides into the codons and anticodons of mRNAs and tRNAs, and...

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Bibliographic Details
Published in:J Am Chem Soc
Main Authors: Feldman, Aaron W., Dien, Vivian T., Karadeema, Rebekah J., Fischer, Emil C., You, Yanbo, Anderson, Brooke A., Krishnamurthy, Ramanarayanan, Chen, Jason S., Li, Lingjun, Romesberg, Floyd E.
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693872/
https://ncbi.nlm.nih.gov/pubmed/31241334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b02075
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