Optimization of Replication, Transcription, and Translation in a Semi-Synthetic Organism

Previously, we reported the creation of a semi-synthetic organism (SSO) that stores and retrieves increased information by virtue of stably maintaining an unnatural base pair (UBP) in its DNA, transcribing the corresponding unnatural nucleotides into the codons and anticodons of mRNAs and tRNAs, and...

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Publicat a:J Am Chem Soc
Autors principals: Feldman, Aaron W., Dien, Vivian T., Karadeema, Rebekah J., Fischer, Emil C., You, Yanbo, Anderson, Brooke A., Krishnamurthy, Ramanarayanan, Chen, Jason S., Li, Lingjun, Romesberg, Floyd E.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693872/
https://ncbi.nlm.nih.gov/pubmed/31241334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b02075
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