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Invader probes: harnessing the energy of intercalation to facilitate recognition of chromosomal DNA for diagnostic applications
Development of probes capable of recognizing specific regions of chromosomal DNA has been a long-standing goal for chemical biologists. Current strategies such as PNA, triplex-forming oligonucleotides, and polyamides are subject to target choice limitations and/or necessitate non-physiological condi...
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| Publicado no: | Chem Sci |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4521421/ https://ncbi.nlm.nih.gov/pubmed/26240741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc01238d |
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