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Recognition of mixed-sequence DNA duplexes: Design guidelines for Invaders based on 2′-O-(pyren-1-yl)methyl-RNA monomers
Development of agents that recognize mixed-sequence double-stranded DNA (dsDNA) is desirable due to their potential as tools for detection, regulation and modification of genes. Despite progress with triplex-forming oligonucleotides, peptide nucleic acids, polyamides and other approaches, recognitio...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3903098/ https://ncbi.nlm.nih.gov/pubmed/24195730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo402085v |
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