Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives

Por Anguiano, Jaime, Garner, Thomas P, Mahalingam, Murugesan, Das, Bhaskar C., Gavathiotis, Evripidis, Cuervo, Ana Maria
Publicado em 2013

A Kazal-Type Serine Protease Inhibitor from the Defense Gland Secretion of the Subterranean Termite Coptotermes formosanus Shiraki

Por Negulescu, Horia, Guo, Youzhong, Garner, Thomas P., Goodwin, Octavia Y., Henderson, Gregg, Laine, Roger A., Macnaughtan, Megan A.
Publicado no PLoS One (2015)

Design, Synthesis and Evaluation of Marinopyrrole Derivatives as Selective Inhibitors of Mcl-1 Binding to Pro-apoptotic Bim and Dual Mcl-1/Bcl-xL Inhibitors

Por Li, Rongshi, Cheng, Chunwei, Balasis, Maria E., Liu, Yan, Garner, Thomas P., Daniel, Kenyon G., Li, Jerry, Qin, Yong, Gavathiotis, Evripidis, Sebti, Said M.
Publicado no Eur J Med Chem (2014)

Rumi functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase

Por Takeuchi, Hideyuki, Fernández-Valdivia, Rodrigo C., Caswell, Devin S., Nita-Lazar, Aleksandra, Rana, Nadia A., Garner, Thomas P., Weldeghiorghis, Thomas K., Macnaughtan, Megan A., Jafar-Nejad, Hamed, Haltiwanger, Robert S.
Publicado em 2011

An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway

Por Garner, Thomas P., Reyna, Denis E., Priyadarshi, Amit, Chen, Hui-Chen, Li, Sheng, Wu, Yang, Ganesan, Yogesh Tengarai, Malashkevich, Vladimir N., Almo, Steve S., Cheng, Emily H., Gavathiotis, Evripidis
Publicado no Mol Cell (2016)

Marinopyrrole Derivatives with Sulfide Spacers as Selective Disruptors of Mcl-1 Binding to Pro-Apoptotic Protein Bim

Por Cheng, Chunwei, Liu, Yan, Balasis, Maria E., Garner, Thomas P., Li, Jerry, Simmons, Nicholas L., Berndt, Norbert, Song, Hao, Pan, Lili, Qin, Yong, Nicolaou, K. C., Gavathiotis, Evripidis, Sebti, Said M., Li, Rongshi
Publicado em 2014

Inhibition of Pro-Apoptotic BAX by a Noncanonical Interaction Mechanism

Por Barclay, Lauren A., Wales, Thomas E., Garner, Thomas P., Wachter, Franziska, Lee, Susan, Guerra, Rachel M., Stewart, Michelle L., Braun, Craig R., Bird, Gregory H., Gavathiotis, Evripidis, Engen, John R., Walensky, Loren D.
Publicado no Mol Cell (2015)

On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts

Por Iachettini, Sara, Stevens, Malcolm FG, Frigerio, Mark, Hummersone, Marc G, Hutchinson, Ian, Garner, Thomas P, Searle, Mark S, Wilson, David W, Munde, Manoj, Nanjunda, Rupesh, D’Angelo, Carmen, Zizza, Pasquale, Rizzo, Angela, Cingolani, Chiara, De Cicco, Federica, Porru, Manuela, D’Incalci, Maurizio, Leonetti, Carlo, Biroccio, Annamaria, Salvati, Erica
Publicado em 2013