Depletion of K-Ras promotes proteasome degradation of survivin

Autor Tecleab, Awet, Sebti, Saïd M.
Vydáno 2013

Measurement of protein farnesylation and geranylgeranylation in vitro, in cultured cells and in biopsies, and the effects of prenyl transferase inhibitors

Autor Berndt, Norbert, Sebti, Saïd M
Vydáno 2011

Ral GTPase Down-regulation Stabilizes and Reactivates p53 to Inhibit Malignant Transformation

Autor Tecleab, Awet, Zhang, Xiaolei, Sebti, Said M.
Vydáno v J Biol Chem (2014)

Targeting protein prenylation for cancer therapy

Autor Berndt, Norbert, Hamilton, Andrew D., Sebti, Saïd M.
Vydáno 2011

The GTPase KRAS suppresses the p53 tumor suppressor by activating the NRF2-regulated antioxidant defense system in cancer cells

Autor Yang, Hua, Xiang, Shengyan, Kazi, Aslamuzzaman, Sebti, Said M.
Vydáno v J Biol Chem (2020)

Akt2 and acid ceramidase cooperate to induce cell invasion and resistance to apoptosis

Autor Berndt, Norbert, Patel, Ronil, Yang, Hua, Balasis, Maria E., Sebti, Saïd M.
Vydáno 2013

Identification of novel ROCK inhibitors with anti-migratory and anti-invasive activities

Autor Patel, Ronil A., Liu, Yan, Wang, Binglin, Li, Rongshi, Sebti, Saïd M.
Vydáno 2013

p21(WAF1/CIP1) Is Upregulated by the Geranylgeranyltransferase I Inhibitor GGTI-298 through a Transforming Growth Factor β- and Sp1-Responsive Element: Involvement of the Small G...

Autor Adnane, Jalila, Bizouarn, Francisco A., Qian, Yimin, Hamilton, Andrew D., Sebti, Saïd M.
Vydáno 1998

Identification of novel inhibitors that disrupt STAT3/DNA interaction from γ-AApeptide OBOC combinatorial library

Autor Teng, Peng, Zhang, Xiaolei, Wu, Haifan, Qiao, Qiao, Sebti, Said M., Cai, Jianfeng
Vydáno 2014

A Phase I Study of GGTI-2418 (Geranylgeranyl Transferase I Inhibitor) in Patients with Advanced Solid Tumors

Autor Karasic, Thomas B., Chiorean, E. Gabriela, Sebti, Said M., O’Dwyer, Peter J.
Vydáno v Target Oncol (2019)

Targeting Protein Tyrosine Phosphatases for Anticancer Drug Discovery

Autor Scott, Latanya. M., Lawrence, Harshani. R., Sebti, Saïd. M., Lawrence, Nicholas. J., Wu, Jie.
Vydáno 2010

Discovery of PI-1840, a Novel Noncovalent and Rapidly Reversible Proteasome Inhibitor with Anti-tumor Activity

Autor Kazi, Aslamuzzaman, Ozcan, Sevil, Tecleab, Awet, Sun, Ying, Lawrence, Harshani R., Sebti, Saïd M.
Vydáno 2014

Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacological selective inhibition of the Jak2/STAT3 pathway

Autor Nefedova, Yulia, Nagaraj, Srinivas, Rosenbauer, Amsler, Muro-Cacho, Carlos, Sebti, Said M., Gabrilovich, Dmitry I.
Vydáno 2005

Vitamin E δ-Tocotrienol Augments the Anti-tumor Activity of Gemcitabine and Suppresses Constitutive NF-κB Activation in Pancreatic Cancer

Autor Husain, Kazim, Francois, Rony A., Yamauchi, Teruo, Perez, Marta, Sebti, Said M., Malafa, Mokenge P.
Vydáno 2011

δ-Tocotrienol, a natural form of vitamin E, inhibits pancreatic cancer stem-like cells and prevents pancreatic cancer metastasis

Autor Husain, Kazim, Centeno, Barbara A, Coppola, Domenico, Trevino, Jose, Sebti, Said M, Malafa, Mokenge P
Vydáno v Oncotarget (2017)

Regulation of Matrix Metalloproteinase Genes by E2F transcription factors: Rb-Raf-1 interaction as a novel target for metastatic disease

Autor Johnson, Jackie L., Pillai, Smitha, Pernazza, Danielle, Sebti, Said M., Lawrence, Nicholas J., Chellappan, Srikumar P.
Vydáno 2011

Activation of dendritic cells via inhibition of Jak2/STAT3 signaling

Autor Nefedova, Yulia, Cheng, Pingyan, Gilkes, Daniele, Blaskovich, Michelle, Beg, Amer A., Sebti, Said M., Gabrilovich, Dmitry I.
Vydáno 2005

Lysophosphatidic Acid Acyltransferase Beta Regulates mTOR Signaling

Autor Blaskovich, Michelle A., Yendluri, Vimala, Lawrence, Harshani R., Lawrence, Nicholas J., Sebti, Saïd M., Springett, Gregory M.
Vydáno 2013

Use of Proximity Ligation to Screen for Inhibitors of Interactions between Vascular Endothelial Growth Factor A and Its Receptors

Autor Gustafsdottir, Sigrun M., Wennström, Stefan, Fredriksson, Simon, Schallmeiner, Edith, Hamilton, Andrew D., Sebti, Said M., Landegren, Ulf
Vydáno 2008

Vitamin E δ-tocotrienol prolongs survival in the LSL-Kras(G12D/+);LSL-Trp53(R172H/+);Pdx-1-Cre (KPC) transgenic mouse model of pancreatic cancer

Autor Husain, Kazim, Centeno, Barbara A., Chen, Dung-Tsa, Hingorani, Sunil R., Sebti, Said M., Malafa, Mokenge P.
Vydáno 2013