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Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives
Chaperone-mediated autophagy (CMA) contributes to cellular quality control and the cellular response to stress through the selective degradation of cytosolic proteins in lysosomes. Decrease in CMA activity occurs in aging and in age-related disorders (for example, neurodegenerative diseases and diab...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3661710/ https://ncbi.nlm.nih.gov/pubmed/23584676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1230 |
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