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Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives

Chaperone-mediated autophagy (CMA) contributes to cellular quality control and the cellular response to stress through the selective degradation of cytosolic proteins in lysosomes. Decrease in CMA activity occurs in aging and in age-related disorders (for example, neurodegenerative diseases and diab...

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Autori principali: Anguiano, Jaime, Garner, Thomas P, Mahalingam, Murugesan, Das, Bhaskar C., Gavathiotis, Evripidis, Cuervo, Ana Maria
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3661710/
https://ncbi.nlm.nih.gov/pubmed/23584676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1230
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