Minor groove to major groove, an unusual DNA sequence dependent change in bend directionality by a distamycin dimer

Por Wang, Shuo, Munde, Manoj, Wang, Siming, Wilson, W. David
Publicado em 2011

Probing the electrostatics and pharmacologic modulation of sequence-specific binding by the DNA-binding domain of the ETS-family transcription factor PU.1: a binding affinity and k...

Por Munde, Manoj, Poon, Gregory M. K., Wilson, W. David
Publicado em 2013

Complexity in the binding of minor groove agents: netropsin has two thermodynamically different DNA binding modes at a single site

Por Lewis, Edwin A., Munde, Manoj, Wang, Shuo, Rettig, Michael, Le, Vu, Machha, Venkata, Wilson, W. David
Publicado em 2011

Mechanistic Heterogeneity in Site Recognition by the Structurally Homologous DNA-binding Domains of the ETS Family Transcription Factors Ets-1 and PU.1

Por Wang, Shuo, Linde, Miles H., Munde, Manoj, Carvalho, Victor D., Wilson, W. David, Poon, Gregory M. K.
Publicado em 2014

Induced Fit Conformational Changes of a “Reversed Amidine” Heterocycle: Optimized Interactions in a DNA Minor Groove Complex

Por Munde, Manoj, Lee, Michael, Neidle, Stephen, Arafa, Reem, Boykin, David W., Liu, Yang, Bailly, Christian, Wilson, W. David
Publicado em 2007

Novel linear triaryl guanidines, N-substituted guanidines and potential prodrugs as antiprotozoal agents

Por Arafa, Reem K., Ismail, Mohamed A., Munde, Manoj, Wilson, W. David, Wenzler, Tanja, Brun, Reto, Boykin, David W.
Publicado em 2008

Green Fluorescent Diamidines as Diagnostic Probes for Trypanosomes

Por Giordani, Federica, Munde, Manoj, Wilson, W. David, Ismail, Mohamed A., Kumar, Arvind, Boykin, David W., Barrett, Michael P.
Publicado em 2014

Microscopic Rearrangement of Bound Minor Groove Binders Detected by NMR

Por Rettig, Michael, Germann, Markus W., Ismail, Mohamed A., Batista-Parra, Adalgisa, Munde, Manoj, Boykin, David W., Wilson, W. David
Publicado em 2012

Synthesis and activity of azaterphenyl diamidines against Trypanosoma brucei rhodesiense and Plasmodium falciparum

Por Hu, Laixing, Arafa, Reem K., Ismail, Mohamed A., Patel, Alpa, Munde, Manoj, Wilson, W. David, Wenzler, Tanja, Brun, Reto, Boykin, David W.
Publicado em 2009

Structure-dependent inhibition of the ETS-family transcription factor PU.1 by novel heterocyclic diamidines

Por Munde, Manoj, Wang, Shuo, Kumar, Arvind, Stephens, Chad E., Farahat, Abdelbasset A., Boykin, David W., Wilson, W. David, Poon, Gregory M. K.
Publicado em 2014

Synthesis and Antiprotozoal Activity of Dicationic 2, 6-Diphenylpyrazines and Aza-Analogues

Por Hu, Laixing, Patel, Alpa, Bondada, Lavanya, Yang, Sihyung, Wang, Michael Zhuo, Munde, Manoj, Wilson, W. David, Wenzler, Tanja, Brun, Reto, Boykin, David W.
Publicado em 2013

Synthesis, DNA binding and antileishmanial activity of low molecular weight bis-arylimidamides

Por Banerjee, Moloy, Farahat, Abdelbasset A., Kumar, Arvind, Wenzler, Tanja, Brun, Reto, Munde, Manoj M., Wilson, W. David, Zhu, Xiaohua, Werbovetz, Karl A., Boykin, David W.
Publicado em 2012

Induced topological changes in DNA complexes: influence of DNA sequences and small molecule structures

Por Hunt, Rebecca A., Munde, Manoj, Kumar, Arvind, Ismail, Mohamed A., Farahat, Abdelbasset A., Arafa, Reem K., Say, Martial, Batista-Parra, Adalgisa, Tevis, Denise, Boykin, David W., Wilson, W. David
Publicado em 2011

The Unusual Monomer Recognition of Guanine-Containing Mixed Sequence DNA by a Dithiophene Heterocyclic Diamidine

Por Munde, Manoj, Kumar, Arvind, Peixoto, Paul, Depauw, Sabine, Ismail, Mohamed A., Farahat, Abdelbasset A., Paul, Ananya, Say, Martial V., David-Cordonnier, Marie-Hélène, Boykin, David W., Wilson, W. David
Publicado em 2014

DNA Minor Groove Induced Dimerization of Heterocyclic Cations: Compound Structure, Binding Affinity and Specificity for a TTAA Site

Por Munde, Manoj, Kumar, Arvind, Nhili, Raja, Depauw, Sabine, David-Cordonnier, Marie-Hélène, Ismail, Mohamed A., Stephens, Chad E., Farahat, Abdelbasset A., Batista-Parra, Adalgisa, Boykin, David W., Wilson, W. David
Publicado em 2010

Design of DNA Minor Groove Binding Diamidines that Recognize GC base pair Sequences: A Dimeric-Hinge Interaction Motif

Por Munde, Manoj, Ismail, Mohamed A., Arafa, Reem, Peixoto, Paul, Collar, Catharine J., Liu, Yang, Hu, Laixing, David-Cordonnier, Marie-Hélène, Lansiaux, Amélie, Bailly, Christian, Boykin, David W., Wilson, W. David
Publicado em 2007

Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines

Por Nhili, Raja, Peixoto, Paul, Depauw, Sabine, Flajollet, Sébastien, Dezitter, Xavier, Munde, Manoj M., Ismail, Mohamed A., Kumar, Arvind, Farahat, Abdelbasset A., Stephens, Chad E., Duterque-Coquillaud, Martine, David Wilson, W., Boykin, David W., David-Cordonnier, Marie-Hélène
Publicado em 2013

Structure Dependent Binding of Arylimidamides to the DNA Minor Groove

Por Chai, Yun, Munde, Manoj, Kumar, Arvind, Mickelson, Leah, Lin, Sen, Campbell, Nancy H., Banerjee, Moloy, Akay, Senol, Liu, Zongying, Farahat, Abdelbasset A., Nhili, Raja, Depauw, Sabine, David-Cordonnier, Marie-Hélène, Neidle, Stephen, Wilson, W. David, Boykin, David W.
Publicado em 2013

Novel Arylimidamides for Treatment of Visceral Leishmaniasis

Por Wang, Michael Zhuo, Zhu, Xiaohua, Srivastava, Anuradha, Liu, Qiang, Sweat, J. Mark, Pandharkar, Trupti, Stephens, Chad E., Riccio, Ed, Parman, Toufan, Munde, Manoj, Mandal, Swati, Madhubala, Rentala, Tidwell, Richard R., Wilson, W. David, Boykin, David W., Hall, James Edwin, Kyle, Dennis E., Werbovetz, Karl A.
Publicado em 2010

On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts

Por Iachettini, Sara, Stevens, Malcolm FG, Frigerio, Mark, Hummersone, Marc G, Hutchinson, Ian, Garner, Thomas P, Searle, Mark S, Wilson, David W, Munde, Manoj, Nanjunda, Rupesh, D’Angelo, Carmen, Zizza, Pasquale, Rizzo, Angela, Cingolani, Chiara, De Cicco, Federica, Porru, Manuela, D’Incalci, Maurizio, Leonetti, Carlo, Biroccio, Annamaria, Salvati, Erica
Publicado em 2013