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Induced Fit Conformational Changes of a “Reversed Amidine” Heterocycle: Optimized Interactions in a DNA Minor Groove Complex
To better understand the molecular basis for recognition of the DNA minor groove by heterocyclic cations, a series of “reversed amidine” substituted heterocycles has been prepared. Amidine derivatives for targeting the minor groove have the amidine carbon linked to a central heterocyclic system whil...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2547086/ https://ncbi.nlm.nih.gov/pubmed/17425312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja069003n |
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