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Microscopic Rearrangement of Bound Minor Groove Binders Detected by NMR

Thermodynamic and structural studies are commonly utilized to optimize small molecules for specific DNA interactions and thus, a significant amount of binding data is available. However, the dynamic processes that are involved in minor groove complex formation and maintenance are not fully understoo...

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Detalhes bibliográficos
Main Authors: Rettig, Michael, Germann, Markus W., Ismail, Mohamed A., Batista-Parra, Adalgisa, Munde, Manoj, Boykin, David W., Wilson, W. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637426/
https://ncbi.nlm.nih.gov/pubmed/22530735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp301143e
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