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Heterocyclic Diamidine Interactions at AT Base Pairs in the DNA Minor Groove: Effects of Heterocycle Differences, DNA AT Sequence and Length

Given the increasing significance of diamidines as DNA–targeted therapeutics and biotechnology reagents, it is important to establish the variations in thermodynamic quantities that characterize the interactions of closely related compounds to different sequence AT binding sites. In this study, an a...

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書誌詳細
主要な著者: Liu, Yang, Collar, Catharine J., Kumar, Arvind, Stephens, Chad E., Boykin, David W., Wilson, W. David
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556899/
https://ncbi.nlm.nih.gov/pubmed/18717551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp804048c
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