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Heterocyclic Diamidine Interactions at AT Base Pairs in the DNA Minor Groove: Effects of Heterocycle Differences, DNA AT Sequence and Length

Given the increasing significance of diamidines as DNA–targeted therapeutics and biotechnology reagents, it is important to establish the variations in thermodynamic quantities that characterize the interactions of closely related compounds to different sequence AT binding sites. In this study, an a...

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Detalhes bibliográficos
Main Authors: Liu, Yang, Collar, Catharine J., Kumar, Arvind, Stephens, Chad E., Boykin, David W., Wilson, W. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556899/
https://ncbi.nlm.nih.gov/pubmed/18717551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp804048c
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