Design of DNA Minor Groove Binding Diamidines that Recognize GC base pair Sequences: A Dimeric-Hinge Interaction Motif

The classical model of DNA minor groove binding compounds is that they should have a crescent shape that closely fits the helical twist of the groove. Several compounds with relatively linear shape and large dihedral twist, however, have been found recently to bind strongly to the minor groove. Thes...

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Autori principali: Munde, Manoj, Ismail, Mohamed A., Arafa, Reem, Peixoto, Paul, Collar, Catharine J., Liu, Yang, Hu, Laixing, David-Cordonnier, Marie-Hélène, Lansiaux, Amélie, Bailly, Christian, Boykin, David W., Wilson, W. David
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865524/
https://ncbi.nlm.nih.gov/pubmed/17935330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja074560a
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