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A New Generation of Minor-Groove-Binding—Heterocyclic Diamidines That Recognize G·C Base Pairs in an AT Sequence Context

We review the preparation of new compounds with good solution and cell uptake properties that can selectively recognize mixed A·T and G·C bp sequences of DNA. Our underlying aim is to show that these new compounds provide important new biotechnology reagents as well as a new class of therapeutic can...

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Publicat a:Molecules
Autors principals: Paul, Ananya, Guo, Pu, Boykin, David W., Wilson, W. David
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429135/
https://ncbi.nlm.nih.gov/pubmed/30866557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24050946
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