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A New Generation of Minor-Groove-Binding—Heterocyclic Diamidines That Recognize G·C Base Pairs in an AT Sequence Context

We review the preparation of new compounds with good solution and cell uptake properties that can selectively recognize mixed A·T and G·C bp sequences of DNA. Our underlying aim is to show that these new compounds provide important new biotechnology reagents as well as a new class of therapeutic can...

詳細記述

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書誌詳細
出版年:Molecules
主要な著者: Paul, Ananya, Guo, Pu, Boykin, David W., Wilson, W. David
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6429135/
https://ncbi.nlm.nih.gov/pubmed/30866557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24050946
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