Sequence and Length Dependent Thermodynamic Differences in Heterocyclic Diamidine Interactions at AT Base Pairs in the DNA Minor Groove

With the goal of developing a better understanding of the antiparasitic biological action of DB75, we have evaluated its interaction with duplex alternating and nonalternating sequence AT polymers and oligomers. These DNAs provide an important pair of sequences in a detailed thermodynamic analysis o...

Full description

Saved in:
Bibliographic Details
Main Authors: Liu, Yang, Kumar, Arvind, Boykin, David W., Wilson, W. David
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291445/
https://ncbi.nlm.nih.gov/pubmed/17889984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2007.08.007
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items