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Small Size Sequence-sensitive Compounds for Specific Recognition of G·C Base Pair in DNA Minor Groove.
A novel series of small size diamidines with thiophene and modified N-alkylbenzimidazole σ-hole module represent specific binding to single G·C base pair (bp) DNA sequence. The variation of N-alkyl or aromatic rings were sensitive to microstructure of DNA minor groove. Thirteen new compounds were sy...
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| Published in: | Chemistry |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7265973/ https://ncbi.nlm.nih.gov/pubmed/31884714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201904396 |
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