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Extending the σ-Hole Motif for Sequence Specific Recognition of the DNA Minor Groove
The majority of current drugs against diseases, such as cancer, can bind to one or more sites in a protein and inhibit its activity. There are, however, well known limits on the number of druggable proteins and complementing current drugs with compounds that could selectively target DNA or RNA would...
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| Опубликовано в: : | Biochemistry |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7849046/ https://ncbi.nlm.nih.gov/pubmed/32293884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00090 |
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