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Small Size Sequence-sensitive Compounds for Specific Recognition of G·C Base Pair in DNA Minor Groove.

A novel series of small size diamidines with thiophene and modified N-alkylbenzimidazole σ-hole module represent specific binding to single G·C base pair (bp) DNA sequence. The variation of N-alkyl or aromatic rings were sensitive to microstructure of DNA minor groove. Thirteen new compounds were sy...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Chemistry
Egile Nagusiak: Farahat, Abdelbasset A., Guo, Pu, Shoeib, Hadir, Paul, Ananya, Boykin, David W., Wilson, W. David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7265973/
https://ncbi.nlm.nih.gov/pubmed/31884714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201904396
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