Crystalline and Amorphous Preparation of Aluminum Hydroxide Nanoparticles Enhances Protective Antigen Domain 4 Specific Immunogenicity and Provides Protection Against Anthrax

INTRODUCTION: Aluminum salts, although they have been used as adjuvants in many vaccine formulations since 1926, exclusively induce a Th2-biased immune response, thereby limiting their use against intracellular pathogens like Mycobacterium tuberculosis. METHODS AND RESULTS: Herein, we synthesized am...

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Dettagli Bibliografici
Pubblicato in:Int J Nanomedicine
Autori principali: Gogoi, Himanshu, Mani, Rajesh, Aggarwal, Soumya, Malik, Anshu, Munde, Manoj, Bhatnagar, Rakesh
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove 2020
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6970252/
https://ncbi.nlm.nih.gov/pubmed/32021177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S219647
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