Structural and Immunological Analysis of Anthrax Recombinant Protective Antigen Adsorbed to Aluminum Hydroxide Adjuvant

New anthrax vaccines currently under development are based on recombinant protective antigen (rPA) and formulated with aluminum adjuvant. Because long-term stability is a desired characteristic of these vaccines, an understanding of the effects of adsorption to aluminum adjuvants on the structure of...

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Main Authors: Wagner, Leslie, Verma, Anita, Meade, Bruce D., Reiter, Karine, Narum, David L., Brady, Rebecca A., Little, Stephen F., Burns, Drusilla L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Vaccines
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428410/
https://ncbi.nlm.nih.gov/pubmed/22815152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00174-12
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