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Minor groove to major groove, an unusual DNA sequence dependent change in bend directionality by a distamycin dimer

DNA sequence dependent conformational changes induced by the minor groove binder, distamycin, have been evaluated by polyacrylamide gel electrophoresis. The distamycin binding affinity, cooperativity and stoichiometry with three target DNA sequences that have different sizes of alternating AT sites,...

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Detalhes bibliográficos
Main Authors: Wang, Shuo, Munde, Manoj, Wang, Siming, Wilson, W. David
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164995/
https://ncbi.nlm.nih.gov/pubmed/21800847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201010g
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