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Minor groove to major groove, an unusual DNA sequence dependent change in bend directionality by a distamycin dimer
DNA sequence dependent conformational changes induced by the minor groove binder, distamycin, have been evaluated by polyacrylamide gel electrophoresis. The distamycin binding affinity, cooperativity and stoichiometry with three target DNA sequences that have different sizes of alternating AT sites,...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3164995/ https://ncbi.nlm.nih.gov/pubmed/21800847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi201010g |
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