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Steered molecular dynamics simulations on the "tail helix latch" hypothesis in the gelsolin activation process.

The molecular basis of the "tail helix latch" hypothesis in the gelsolin activation process has been studied by using the steered molecular dynamics simulations. In the present nanosecond scale simulations, the tail helix of gelsolin was pulled away from the S2 binding surface, and the req...

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Autors principals: Cheng, Feng, Shen, Jianhua, Luo, Xiaomin, Jiang, Hualiang, Chen, Kaixian
Format: Artigo
Idioma:Inglês
Publicat: 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302184/
https://ncbi.nlm.nih.gov/pubmed/12124262
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