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Ligand-binding regulation of LXR/RXR and LXR/PPAR heterodimerizations: SPR technology-based kinetic analysis correlated with molecular dynamics simulation

Liver X receptor (LXR) and peroxisome proliferator-activated receptor (PPAR) are two members of nuclear receptors involved in the nutrient metabolisms of dietary fatty acid and cholesterol. They are found to be of cross-talk function in that LXR regulates fatty acid synthesis and PPAR controls fatty...

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Main Authors: Yue, Liduo, Ye, Fei, Gui, Chunshan, Luo, Haibin, Cai, Jianhua, Shen, Jianhua, Chen, Kaixian, Shen, Xu, Jiang, Hualiang
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279270/
https://ncbi.nlm.nih.gov/pubmed/15722453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04951405
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