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Ligand-activated PPARβ efficiently represses the induction of LXR-dependent promoter activity through competition with RXR

Angiopoietin-like protein 3 (angptl3), a member of the vascular endothelial growth factor family, was shown to play an important role in regulating lipid metabolism. To elucidate the mechanism by which PPARβ represses angptl3 promoter activity, reporter constructs were prepared and transfection anal...

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Detalhes bibliográficos
Main Authors: Matsusue, Kimihiko, Miyoshi, Aya, Yamano, Shigeru, Gonzalez, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544360/
https://ncbi.nlm.nih.gov/pubmed/16806672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2006.05.005
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