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Ligand-activated PPARβ efficiently represses the induction of LXR-dependent promoter activity through competition with RXR

Angiopoietin-like protein 3 (angptl3), a member of the vascular endothelial growth factor family, was shown to play an important role in regulating lipid metabolism. To elucidate the mechanism by which PPARβ represses angptl3 promoter activity, reporter constructs were prepared and transfection anal...

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Autori principali: Matsusue, Kimihiko, Miyoshi, Aya, Yamano, Shigeru, Gonzalez, Frank J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544360/
https://ncbi.nlm.nih.gov/pubmed/16806672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2006.05.005
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