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Hepatic steatosis in leptin-deficient mice is promoted by the PPARγ target gene, fat-specific protein 27
PPARγ is induced in leptin-deficient mouse (ob/ob) liver and is critical for the development of hepatic steatosis. The present study shows that fsp27 in ob/ob liver is a direct target gene of PPARγ and can elevate hepatic triglyceride levels. Fsp27 belongs to the cide family, composed of cide a, cid...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587176/ https://ncbi.nlm.nih.gov/pubmed/18396136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2008.03.003 |
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