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Effects of rupatadine, a new dual antagonist of histamine and platelet-activating factor receptors, on human cardiac Kv1.5 channels

1. The effects of rupatadine, a new dual antagonist of both histamine H(1) and platelet-activating factor receptors, were studied on human cloned hKv1.5 channels expressed in Ltk(−) cells using the whole-cell patch-clamp technique. 2. Rupatadine produced a use- and concentration-dependent block of h...

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Autori principali: Caballero, Ricardo, Valenzuela, Carmen, Longobardo, Mónica, Tamargo, Juan, Delpón, Eva
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571731/
https://ncbi.nlm.nih.gov/pubmed/10556945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702890
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