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Effects of propafenone and 5-hydroxy-propafenone on hKv1.5 channels

1. The goal of this study was to analyse the effects of propafenone and its major metabolite, 5-hydroxy-propafenone, on a human cardiac K(+) channel (hKv1.5) stably expressed in Ltk(−) cells and using the whole-cell configuration of the patch-clamp technique. 2. Propafenone and 5-hydroxy-propafenone...

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Detalhes bibliográficos
Main Authors: Franqueza, Laura, Valenzuela, Carmen, Delpón, Eva, Longobardo, Mónica, Caballero, Ricardo, Tamargo, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565661/
https://ncbi.nlm.nih.gov/pubmed/9846634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702129
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