Učitavanje...
Second coiled-coil domain of KCNQ channel controls current expression and subfamily specific heteromultimerization by salt bridge networks
KCNQ channels carry the slowly activating, voltage-dependent M-current in excitable cells such as neurons. Although the KCNQ2 homomultimer can form a functional voltage-gated K(+) channel, heteromultimerization with KCNQ3 produces a > 10-fold increase in current amplitude. All KCNQ channels conta...
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Glavni autori: | , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Blackwell Science Inc
2008
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2517212/ https://ncbi.nlm.nih.gov/pubmed/18440995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.148601 |
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