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KCNE1 and KCNE3 Stabilize and/or Slow Voltage Sensing S4 Segment of KCNQ1 Channel

KCNQ1 is a voltage-dependent K(+) channel whose gating properties are dramatically altered by association with auxiliary KCNE proteins. For example, KCNE1, which is mainly expressed in heart and inner ear, markedly slows the activation kinetics of KCNQ1. Whether the voltage-sensing S4 segment moves...

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Detalhes bibliográficos
Main Authors: Nakajo, Koichi, Kubo, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151641/
https://ncbi.nlm.nih.gov/pubmed/17698596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709805
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