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Stoichiometry of the KCNQ1 - KCNE1 ion channel complex

The KCNQ1 voltage-gated potassium channel and its auxiliary subunit KCNE1 play a crucial role in the regulation of the heartbeat. The stoichiometry of KCNQ1 and KCNE1 complex has been debated, with some results suggesting that the four KCNQ1 subunits that form the channel associate with two KCNE1 su...

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Bibliografiske detaljer
Main Authors: Nakajo, Koichi, Ulbrich, Maximilian H., Kubo, Yoshihiro, Isacoff, Ehud Y.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973890/
https://ncbi.nlm.nih.gov/pubmed/20962273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010354107
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