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Stoichiometry of the KCNQ1 - KCNE1 ion channel complex

The KCNQ1 voltage-gated potassium channel and its auxiliary subunit KCNE1 play a crucial role in the regulation of the heartbeat. The stoichiometry of KCNQ1 and KCNE1 complex has been debated, with some results suggesting that the four KCNQ1 subunits that form the channel associate with two KCNE1 su...

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Autors principals: Nakajo, Koichi, Ulbrich, Maximilian H., Kubo, Yoshihiro, Isacoff, Ehud Y.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973890/
https://ncbi.nlm.nih.gov/pubmed/20962273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010354107
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