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Pharmacological Properties and Functional Role of K(slow) Current in Mouse Pancreatic β-Cells: SK Channels Contribute to K(slow) Tail Current and Modulate Insulin Secretion
The pharmacological properties of slow Ca(2+)-activated K(+) current (K(slow)) were investigated in mouse pancreatic β-cells and islets to understand how K(slow) contributes to the control of islet bursting, [Ca(2+)](i) oscillations, and insulin secretion. K(slow) was insensitive to apamin or the K(...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2266621/ https://ncbi.nlm.nih.gov/pubmed/16186562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200509312 |
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