Structure–Activity Studies of Divin: An Inhibitor of Bacterial Cell Division

Por Zhou, Maoquan, Eun, Ye-Jin, Guzei, Ilia A., Weibel, Douglas B.
Publicado em 2013

The Scene Time Interval and Basic Life Support Termination of Resuscitation Rule in Adult Out-of-Hospital Cardiac Arrest

Por Kim, Tae Han, Shin, Sang Do, Kim, Yu Jin, Kim, Chu Hyun, Kim, Jeong Eun
Publicado no J Korean Med Sci (2015)

Lung function in our aging population

Por Marek, W, Marek, EM, Mückenhoff, K, Smith, H-J, Kotschy-Lang, N, KohlMäufl, M
Publicado em 2011

A systematic review of animal models for Staphylococcus aureus osteomyelitis

Por Reizner, W., Hunter, J.G., O’Malley, N.T., Southgate, R.D., Schwarz, E.M., Kates, S.L.
Publicado no Eur Cell Mater (2014)

Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors

Por Zhu, Jin-Yi, Cuellar, Rebecca A., Berndt, Norbert, Lee, Hee Eun, Olesen, Sanne H., Martin, Mathew P., Jensen, Jeffrey T., Georg, Gunda I., Schönbrunn, Ernst
Publicado no J Med Chem (2017)

Heterosubtypic protective immunity against widely divergent influenza subtypes induced by fusion protein 4sM2 in BALB/c mice

Por Chowdhury, Mohammed YE, Seo, Soo-Kyung, Moon, Ho-Jin, Talactac, Melbourne R, Kim, Jae-Hoon, Park, Min-Eun, Son, Hwa-Young, Lee, Jong-Soo, Kim, Chul-Joong
Publicado em 2014

Vitrification of mouse embryos using the thin plastic strip method

Por Ryu, Eun Kyung, Hur, Yong Soo, Ann, Ji Young, Maeng, Ja Young, Park, Miji, Park, Jeong Hyun, Yoon, Jung, Yoon, San Hyun, Hur, Chang Young, Lee, Won Don, Lim, Jin Ho
Publicado em 2012

Tat-DJ-1 inhibits oxidative stress-mediated RINm5F cell death through suppression of NF-κB and MAPK activation

Por Jo, Hyo Sang, Cha, Hyun Ju, Kim, Sang Jin, Yeo, Hyeon Ji, Cho, Su Bin, Park, Jung Hwan, Lee, Chi Hern, Yeo, Eun Ji, Choi, Yeon Joo, Eum, Won Sik, Choi, Soo Young
Publicado no Med Chem Res (2016)

Corrigendum to “Synthesis and cytotoxic activity of novel Aring cleaved ursolic acid derivatives in human nonsmall cell lung cancer cells” [Eur. J. Med. Chem. 123 (2016) 317–331]

Por Mendes, Vanessa I. S., Bartholomeusz, Geoffrey A., Ayres, Mary, Gandhi, Varsha, Salvador, Jorge A. R.
Publicado no Eur J Med Chem (2016)

Discovery of 5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)quinazolin-4-amine as a Potent I(Kur) Inhibitor

Por Finlay, Heather J., Johnson, James A., Lloyd, John L., Jiang, Ji, Neels, James, Gunaga, Prashantha, Banerjee, Abhisek, Dhondi, Naveen, Chimalakonda, Anjaneya, Mandlekar, Sandhya, Conder, Mary Lee, Sale, Harinath, Xing, Dezhi, Levesque, Paul, Wexler, Ruth R.
Publicado no ACS Med Chem Lett (2016)

Redox-based probes as tools to monitor oxidized protein tyrosine phosphatases in living cells

Por Garcia, Francisco J., Carroll, Kate S.
Publicado no Eur J Med Chem (2014)

6-alkylsalicylates are selective Tip60 inhibitors and target the acetyl-CoA binding site

Por Ghizzoni, Massimo, Wu, Jiang, Gao, Tielong, Haisma, Hidde J., Dekker, Frank J., Zheng, Y. George
Publicado em 2011

A Molecular Model for Cocaine Binding by the Immunotherapeutic Human/Mouse Chimeric Monoclonal Antibody 2E2

Por Lape, Michael, Paula, Stefan, Ball, William J.
Publicado em 2010

The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity

Por Newton, Rebecca, Bowler, Katherine A., Burns, Emily M., Chapman, Philip J., Fairweather, Emma E., Fritzl, Samantha J.R., Goldberg, Kristin M., Hamilton, Niall M., Holt, Sarah V., Hopkins, Gemma V., Jones, Stuart D., Jordan, Allan M., Lyons, Amanda J., Nikki March, H., McDonald, Neil Q., Maguire, Laura A., Mould, Daniel P., Purkiss, Andrew G., Small, Helen F., Stowell, Alexandra I.J., Thomson, Graeme J., Waddell, Ian D., Waszkowycz, Bohdan, Watson, Amanda J., Ogilvie, Donald J.
Publicado no Eur J Med Chem (2016)

Design of a novel Thiophene Inhibitor of 15-Lipoxygenase-1 with both Anti-inflammatory and Neuroprotective Properties

Por Eleftheriadis, Nikolaos, Poelman, Hessel, Leus, Niek G. J., Honrath, Birgit, Neochoritis, Constantinos G., Dolga, Amalia, Dömling, Alexander, Dekker, Frank J.
Publicado no Eur J Med Chem (2016)

An evaluation of Minor Groove Binders as anti-Trypanosoma brucei brucei therapeutics

Por Scott, Fraser J., Khalaf, Abedawn I., Giordani, Federica, Wong, Pui Ee, Duffy, Sandra, Barrett, Michael, Avery, Vicky M., Suckling, Colin J.
Publicado no Eur J Med Chem (2016)

Structure-Guided Design of Novel Trypanosoma brucei Methionyl-tRNA Synthetase Inhibitors

Por Huang, Wenlin, Zhang, Zhongsheng, Barros-Álvarez, Ximena, Koh, Cho Yeow, Ranade, Ranae M., Gillespie, J. Robert, Creason, Sharon A., Shibata, Sayaka, Verlinde, Christophe L. M. J., Hol, Wim G. J., Buckner, Frederick S., Fan, Erkang
Publicado no Eur J Med Chem (2016)

Biochemical evaluation of virtual screening methods reveals a cell-active inhibitor of the cancer-promoting phosphatases of regenerating liver

Por Hoeger, Birgit, Diether, Maren, Ballester, Pedro J., Köhn, Maja
Publicado no Eur J Med Chem (2014)

Synthesis and pharmacological evaluation of indole-based sigma receptor ligands

Por Mésangeau, Christophe, Amata, Emanuele, Alsharif, Walid, Seminerio, Michael J., Robson, Matthew J., Matsumoto, Rae R., Poupaert, Jacques H., McCurdy, Christopher R.
Publicado em 2011

The relevance of K(i) calculation for bi-substrate enzymes illustrated by kinetic evaluation of a novel lysine (K) acetyltransferase 8 inhibitor

Por Wapenaar, Hannah, van den Bosch, Thea, Leus, Niek G. J., van der Wouden, Petra E., Eleftheriadis, Nikolaos, Hermans, Jos, Hailu, Gebremedhin Solomon, Rotili, Dante, Mai, Antonello, Dömling, Alexander, Bischoff, Rainer, Haisma, Hidde J., Dekker, Frank J.
Publicado no Eur J Med Chem (2017)