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Redox-based probes as tools to monitor oxidized protein tyrosine phosphatases in living cells

Reversible oxidation of protein tyrosine phosphatases (PTPs) has emerged as an important regulatory mechanism whereby reactive oxygen species (ROS) inactivates the PTP and promotes phosphorylation and induction of the signaling cascade. The lack of sensitive and robust methods to directly detect oxi...

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Publicat a:Eur J Med Chem
Autors principals: Garcia, Francisco J., Carroll, Kate S.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254195/
https://ncbi.nlm.nih.gov/pubmed/24974258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2014.06.040
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