Φορτώνει......
Structure-Guided Design of Novel Trypanosoma brucei Methionyl-tRNA Synthetase Inhibitors
A screening hit 1 against Trypanosoma brucei methionyl-tRNA synthetase was optimized using a structure-guided approach. The optimization led to the identification of two novel series of potent inhibitors, the cyclic linker and linear linker series. Compounds of both series were potent in a T. brucei...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Eur J Med Chem |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2016
|
| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5120670/ https://ncbi.nlm.nih.gov/pubmed/27788467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2016.10.024 |
| Ετικέτες: |
Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!
|