Nonpeptide ligands of neuropeptide FF: current status and structural insights

Por Mankus, Jessica V, McCurdy, Christopher R
Publicado em 2012

Computational Study on the Conformations of Mitragynine and Mitragynaline

Por Liu, Haining, McCurdy, Christopher R., Doerksen, Robert J.
Publicado em 2010

Sigma-2 Receptors Play a Role in Cellular Metabolism: Stimulation of Glycolytic Hallmarks by CM764 in Human SK-N-SH Neuroblastoma

Por Nicholson, Hilary, Mesangeau, Christophe, McCurdy, Christopher R., Bowen, Wayne D.
Publicado no J Pharmacol Exp Ther (2016)

Sigma receptor antagonists attenuate acute methamphetamine-induced hyperthermia by a mechanism independent of IL-1β mRNA expression in the hypothalamus

Por Seminerio, Michael J., Robson, Matthew J., McCurdy, Christopher R., Matsumoto, Rae R.
Publicado em 2012

Characterization of CM572, a Selective Irreversible Partial Agonist of the Sigma-2 Receptor with Antitumor Activity

Por Nicholson, Hilary, Comeau, Anthony, Mesangeau, Christophe, McCurdy, Christopher R., Bowen, Wayne D.
Publicado no J Pharmacol Exp Ther (2015)

A 96-well filtration method for radioligand binding analysis of σ receptor ligands

Por Fishback, James A., Rosen, Abigail, Bhat, Rohit, McCurdy, Christopher R., Matsumoto, Rae R.
Publicado em 2012

Neuroprotective targets through which 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79), a sigma receptor ligand, mitigates the effects of metha...

Por Kaushal, Nidhi, Robson, Matthew J., Rosen, Abagail, McCurdy, Christopher R., Matsumoto, Rae R.
Publicado em 2013

Determination of a highly selective mixed-affinity sigma receptor ligand, in rat plasma by ultra performance liquid chromatography mass spectrometry and its application to a pharma...

Por Jamalapuram, Seshulatha, Vuppala, Pradeep K., Mesangeau, Christophe, McCurdy, Christopher R., Avery, Bonnie A.
Publicado em 2011

Synthesis and characterization of [(3)H]-SN56, a novel radioligand for the σ(1) receptor

Por Fishback, James A., Mesangeau, Christophe, Poupaert, Jacques H., McCurdy, Christopher R., Matsumoto, Rae R.
Publicado em 2010

Pharmacological evaluation of SN79, a sigma (σ) receptor ligand, against methamphetamine-induced neurotoxicity in vivo

Por Kaushal, Nidhi, Seminerio, Michael J., Robson, Matthew J., McCurdy, Christopher R., Matsumoto, Rae R.
Publicado em 2012

Structure Activity Relationship Study of benzo[d]thiazol-2(3H)one Based Receptor Ligands

Por Bhat, Rohit, Fishback, James A., Matsumoto, Rae R., Poupaert, Jacques H., McCurdy, Christopher R.
Publicado em 2013

Development and validation of an UPLC-MS/MS method for the determination of 7-hydroxymitragynine, a μ-opioid agonist, in rat plasma and its application to a pharmacokinetic study

Por Vuppala, Pradeep K., Jamalapuram, Seshulatha, Furr, Edward B., McCurdy, Christopher R., Avery, Bonnie A.
Publicado em 2013

Ultra-performance liquid chromatography tandem mass spectrometry method for the determination of AZ66, a sigma receptor ligand, in rat plasma and its application to in vivo pharmac...

Por Jamalapuram, Seshulatha, Vuppala, Pradeep Kumar, Abdelazeem, Ahmed H., McCurdy, Christopher R., Avery, Bonnie A.
Publicado em 2013

Self-treatment of opioid withdrawal using kratom (Mitragynia speciosa korth)

Por Boyer, Edward W., Babu, Kavita M., Adkins, Jessica E., McCurdy, Christopher R., Halpern, John H.
Publicado em 2008

Design, Synthesis and Biological Evaluation of Bivalent Benzoxazolone and Benzothiazolone Ligands as Potential Anti-inflammatory/Analgesic Agents

Por Abdelazeem, Ahmed H., Khan, Shabana I., White, Stephen W., Sufka, Kenneth J., McCurdy, Christopher R.
Publicado no Bioorg Med Chem (2015)

Flavanones from Miconia prasina

Por Tarawneh, Amer H., León, Francisco, Ibrahim, Mohammed A., Pettaway, Sara, McCurdy, Christopher R., Cutler, Stephen J.
Publicado em 2013

Suspected Adulteration of Commercial Kratom Products with 7-Hydroxymitragynine

Por Lydecker, Alicia G., Sharma, Abhisheak, McCurdy, Christopher R., Avery, Bonnie A., Babu, Kavita M., Boyer, Edward W.
Publicado no J Med Toxicol (2016)

A Novel Substituted Piperazine, CM156, Attenuates the Stimulant and Toxic Effects of Cocaine in Mice

Por Xu, Yan-Tong, Kaushal, Nidhi, Shaikh, Jamaluddin, Wilson, Lisa L., Mésangeau, Christophe, McCurdy, Christopher R., Matsumoto, Rae R.
Publicado em 2010

Synthesis and Pharmacological Evaluation of 6-Acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79), a Cocaine Antagonist, in Rodents

Por Kaushal, Nidhi, Robson, Matthew J., Vinnakota, Harsha, Narayanan, Sanju, Avery, Bonnie A., McCurdy, Christopher R., Matsumoto, Rae R.
Publicado em 2011

SN79, a sigma receptor ligand, blocks methamphetamine-induced microglial activation and cytokine upregulation

Por Robson, Matthew J., Turner, Ryan C., Naser, Zachary J., McCurdy, Christopher R., Huber, Jason D., Matsumoto, Rae R.
Publicado em 2013