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Synthesis and characterization of [(3)H]-SN56, a novel radioligand for the σ(1) receptor
The study of the binding characteristics of σ ligands in vivo and in vitro requires radiolabeled probes with high affinity and selectivity. The radioligand presently used for in vitro studies of the σ(1) receptor, [(3)H](+)-pentazocine, has significant limitations; it is difficult to synthesize, has...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726058/ https://ncbi.nlm.nih.gov/pubmed/21130085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2010.10.099 |
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